Serious side effects from Adipex are not common. As the body adjusts to the new medication, however, some people may experience these effects for the first few days:

• dry mouth, or an unpleasant taste in the mouth
• bowel problems, such as diarrhea or constipation
• vomiting or other stomach upset
• drowsiness

If any symptoms last longer than a few days, call a doctor. The symptoms listed below are more serious. Contact a doctor if any of these symptoms should appear:

• increase in blood pressure
• palpitations (skipped beats) in heartbeat
• restlessness
• dizziness
• tremors
• difficulty sleeping
• swelling in legs or ankles

Sometimes, adjusting the dosage is enough to make side effects taper off or go away altogether.